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Article

hnRNP E1 and E2 have distinct roles in modulating HIV-1 gene expression

23 Apr 2007

Abstract excerpt

Pre-mRNA processing, including 5' end capping, splicing, and 3' end cleavage/polyadenylation, are events coordinated by transcription that can influence the subsequent export and translation of mRNAs. Coordination of RNA processing is crucial in retroviruses such as HIV-1, where inefficient splicing and the export of intron-containing RNAs are required for expression of the full complement of viral proteins. RNA...

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PMID: 17451601
DOI: 10.1186/1742-4690-4-28

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