Article
Screening for gene-environment (G×E) interaction using omics data from exposed individuals: an application to gene-arsenic interaction.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2018
Argos Maria, Tong Lin, Roy Shantanu, Sabarinathan Mekala, Ahmed Alauddin, Islam Md Tariqul, Islam Tariqul, Rakibuz-Zaman Muhammad, Sarwar Golam, Shahriar Hasan, Rahman Mahfuzar, Yunus Md, Graziano Joseph H, Jasmine Farzana, Kibriya Muhammad G, Zhou Xiang, Ahsan Habibul, Pierce Brandon L
Abstract excerpt
Identifying gene-environment interactions is a central challenge in the quest to understand susceptibility to complex, multi-factorial diseases. Developing an understanding of how inter-individual variability in inherited genetic variation alters the effects of environmental exposures will enhance our knowledge of disease mechanisms and improve our ability to predict disease and target interventions to high-risk...
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