Gene-arsenic interaction in longitudinal changes of blood pressure: Findings from the Health Effects of Arsenic Longitudinal Study (HEALS) in Bangladesh.

doi:10.1016/j.taap.2015.07.017

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Gene-arsenic interaction in longitudinal changes of blood pressure: Findings from the Health Effects of Arsenic Longitudinal Study (HEALS) in Bangladesh.

Toxicology and applied pharmacology - 1 Oct 2015

Farzan Shohreh F, Karagas Margaret R, Jiang Jieying, Wu Fen, Liu Mengling, Newman Jonathan D, Jasmine Farzana, Kibriya Muhammad G, Paul-Brutus Rachelle, Parvez Faruque, Argos Maria, Scannell Bryan Molly, Eunus Mahbub, Ahmed Alauddin, Islam Tariqul, Rakibuz-Zaman Muhammad, Hasan Rabiul, Sarwar Golam, Slavkovich Vesna, Graziano Joseph, Ahsan Habibul, Chen Yu

Abstract excerpt

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide and mounting evidence indicates that toxicant exposures can profoundly impact on CVD risk. Epidemiologic studies have suggested that arsenic (As) exposure is positively related to increases in blood pressure (BP), a primary CVD risk factor. However, evidence of whether genetic susceptibility can modify the association between...

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PMID: 26220686
DOI: 10.1016/j.taap.2015.07.017
PMCID: PMC4606937

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