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Article

Prevalence of age-related macular degeneration associated genetic risk factors and 4-year progression data in the Irish population.

The British journal of ophthalmology - 1 Dec 2018

Connolly Emma, Rhatigan Maedbh, O'Halloran Aisling M, Muldrew Katherine Alyson, Chakravarthy Usha, Cahill Mark, Kenny Rose Anne, Doyle Sarah L

Abstract excerpt

BACKGROUND/AIMS: Age-related macular degeneration (AMD) is estimated to affect 196 million people >50 years old globally. Prevalence of AMD-associated genetic risk factors and rate of disease progression are unknown in Ireland. METHODS: Prevalence of AMD-associated genetic risk variants, complement factor H (CFH) rs1061170, age-related maculopathy susceptibility 2 (ARMS2) rs10490924, component 3 (C3) rs2230199,...

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Identifiers

PMID: 29453225
DOI: 10.1136/bjophthalmol-2017-311673

Genes

CFH
ARMS2
CFB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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