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G9A promotes gastric cancer metastasis by upregulating ITGB3 in a SET domain-independent manner

15 Feb 2018

Abstract excerpt

Tumor metastasis is the leading cause of death in patients with advanced gastric cancer (GC). Limited therapeutic regimens are available for this condition, which is associated with a poor prognosis, and the mechanisms underlying tumor metastasis remain unclear. In the present study, increased histone methyltransferase G9A expression in GC tissues correlated with advanced stage and shorter overall survival, and...

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PMID: 29449539
DOI: 10.1038/s41419-018-0322-6

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