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Article

STAT3 Pathway in Gastric Cancer: Signaling, Therapeutic Targeting and Future Prospects

12 Jun 2020

Abstract excerpt

Molecular signaling pathways play a significant role in the regulation of biological mechanisms, and their abnormal expression can provide the conditions for cancer development. The signal transducer and activator of transcription 3 (STAT3) is a key member of the STAT proteins and its oncogene role in cancer has been shown. STAT3 is able to promote the proliferation and invasion of cancer cells and induces...

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PMID: 32545648
DOI: 10.3390/biology9060126

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