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Article

Role of upstream stimulatory factor 2 in glutamate dehydrogenase gene transcription.

Journal of molecular endocrinology - 1 Apr 2018

Gaspar Carlos, Silva-Marrero Jonás I, Salgado María C, Baanante Isabel V, Metón Isidoro

Abstract excerpt

Glutamate dehydrogenase (Gdh) plays a central role in ammonia detoxification by catalysing reversible oxidative deamination of l-glutamate into α-ketoglutarate using NAD+ or NADP+ as cofactor. To gain insight into transcriptional regulation of glud, the gene that codes for Gdh, we isolated and characterised the 5' flanking region of glud from gilthead sea bream (Sparus aurata). In addition, tissue distribution,...

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Identifiers

PMID: 29438976
DOI: 10.1530/JME-17-0142

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