Article
Hepatocyte Nuclear Factor 4α (HNF4α) Is a Transcription Factor of Vertebrate Fatty Acyl Desaturase Gene as Identified in Marine Teleost Siganus canaliculatus.
PloS one - 1 Jan 2016
Dong Yewei, Wang Shuqi, Chen Junliang, Zhang Qinghao, Liu Yang, You Cuihong, Monroig Óscar, Tocher Douglas R, Li Yuanyou
Abstract excerpt
Rabbitfish Siganus canaliculatus was the first marine teleost demonstrated to have the capability of biosynthesizing long-chain polyunsaturated fatty acids (LC-PUFA) from C18 precursors, and to possess a Δ4 fatty acyl desaturase (Δ4 Fad) which was the first report in vertebrates, and is a good model for studying the regulatory mechanisms of LC-PUFA biosynthesis in teleosts. In order to understand regulatory...
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