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HIPK2 polymorphisms rs2058265, rs6464214, and rs7456421 were associated with kidney stone disease in Chinese males not females.

Gene - 5 May 2018

Lin Haisong, Zhu Xiujuan, Long Jun, Chen Yang, Xie Yuanliang, Liao Ming, Chen Jianxin, Tian Jiarong, Huang Shengzhu, Tang Ruiqiang, Xian Xiaoying, Wei Suchun, Wang Qiuyan, Mo Zengnan

Abstract excerpt

BACKGROUND AND AIM: Recent studies have shown that genetic factors are involved in the development of kidney stone disease (KSD). A case-control association analysis was performed to investigate the association between homeodomain-interacting protein kinase 2 (HIPK2; OMIM *606868) polymorphisms and KSD. METHODS: A total of 890 KSD patients and 920 healthy subjects were analyzed. Polymorphisms were genotyped using...

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PMID: 29428801
DOI: 10.1016/j.gene.2018.02.020

Genes

HIPK2

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