Article
Klotho gene polymorphism of rs3752472 is associated with the risk of urinary calculi in the population of Han nationality in Eastern China.
Gene - 10 Sept 2013
Xu Chen, Song Ri-jin, Yang Jie, Jiang Bin, Wang Xiao-lan, Wu Wei, Zhang Wei
Abstract excerpt
BACKGROUND/AIMS: The incidence of urolithiasis has considerably increased throughout the world in the last two decades. Clinical researches have showed an association between oxidative stress and stone formation. Emerging evidence indicated a novel function for klotho protein in anti-oxidative stress. In this study, we aimed at investigating a possible relationship between klotho gene polymorphisms and the risk...
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