Article
A Large Deletion in the NSDHL Gene in Labrador Retrievers with a Congenital Cornification Disorder.
G3 (Bethesda, Md.) - 7 Sept 2017
Bauer Anina, De Lucia Michela, Jagannathan Vidhya, Mezzalira Giorgia, Casal Margret L, Welle Monika M, Leeb Tosso
Abstract excerpt
In heterozygous females affected by an X-linked skin disorder, lesions often appear in a characteristic pattern, the so-called Blaschko's lines. We investigated a female Labrador Retriever and her crossbred daughter, which both showed similar clinical lesions that followed Blaschko's lines. The two male littermates of the affected daughter had died at birth, suggesting a monogenic X-chromosomal semidominant mode...
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