Article
Whole-Genome Sequencing of a Canine Family Trio Reveals a FAM83G Variant Associated with Hereditary Footpad Hyperkeratosis.
G3 (Bethesda, Md.) - 8 Jan 2016
Sayyab Shumaila, Viluma Agnese, Bergvall Kerstin, Brunberg Emma, Jagannathan Vidhya, Leeb Tosso, Andersson Göran, Bergström Tomas F
Abstract excerpt
Over 250 Mendelian traits and disorders, caused by rare alleles have been mapped in the canine genome. Although each disease is rare in the dog as a species, they are collectively common and have major impact on canine health. With SNP-based genotyping arrays, genome-wide association studies (GWAS) have proven to be a powerful method to map the genomic region of interest when 10-20 cases and 10-20 controls are...
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