Enhancement of xylose uptake in 2-deoxyglucose tolerant mutant of Saccharomyces cerevisiae.

doi:10.1016/j.jbiosc.2010.12.020

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Article

Enhancement of xylose uptake in 2-deoxyglucose tolerant mutant of Saccharomyces cerevisiae.

Journal of bioscience and bioengineering - 1 May 2011

Kahar Prihardi, Taku Kazuo, Tanaka Shuzo

Abstract excerpt

Chemical mutation of Saccharomyces cerevisiae using ethyl methane sulfonate was performed to enhance its ability of xylose uptake for ethanol production from lignocellulose under microaerobic condition. Among the appeared mutants, the mutant no. 2 (M2) strain screened using inhibitory effects of 2-deoxyglucose (DOG) showed more than 4-fold high ability in xylose uptake compared with the wild type strain, under...

Topics

Aldehyde Reductase
Catabolite Repression
Deoxyglucose
Ethanol
Fermentation
Glucose
Glucosephosphate Dehydrogenase
Hexokinase
Metabolomics
Mutagenesis
Mutation
Pentosephosphates
Saccharomyces cerevisiae
Sugar Phosphates
Trehalose
Xylitol
Xylose

Source

Open in PubMed

Identifiers

PMID: 21257343
DOI: 10.1016/j.jbiosc.2010.12.020

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