Article
Unraveling the genetic basis of xylose consumption in engineered Saccharomyces cerevisiae strains.
Scientific reports - 21 Dec 2016
Dos Santos Leandro Vieira, Carazzolle Marcelo Falsarella, Nagamatsu Sheila Tiemi, Sampaio Nádia Maria Vieira, Almeida Ludimila Dias, Pirolla Renan Augusto Siqueira, Borelli Guilherme, Corrêa Thamy Lívia Ribeiro, Argueso Juan Lucas, Pereira Gonçalo Amarante Guimarães
Abstract excerpt
The development of biocatalysts capable of fermenting xylose, a five-carbon sugar abundant in lignocellulosic biomass, is a key step to achieve a viable production of second-generation ethanol. In this work, a robust industrial strain of Saccharomyces cerevisiae was modified by the addition of essential genes for pentose metabolism. Subsequently, taken through cycles of adaptive evolution with selection for...
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