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Phylogeographic diversity and mosaicism of the Helicobacter pylori tfs integrative and conjugative elements

26 Jan 2018

Abstract excerpt

The genome of the gastric pathogen Helicobacter pylori is characterised by considerable variation of both gene sequence and content, much of which is contained within three large genomic islands comprising the cag pathogenicity island ( cag PAI) and two mobile integrative and conjugative elements (ICEs) termed tfs3 and tfs4 . All three islands are implicated as virulence factors, although whereas the cag PAI is...

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PMID: 29416569
DOI: 10.1186/s13100-018-0109-4

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