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Article

Vitamin D-Binding Protein Polymorphisms, 25-Hydroxyvitamin D, Sunshine and Multiple Sclerosis.

Nutrients - 7 Feb 2018

Langer-Gould Annette, Lucas Robyn M, Xiang Anny H, Wu Jun, Chen Lie H, Gonzales Edlin, Haraszti Samantha, Smith Jessica B, Quach Hong, Barcellos Lisa F

Abstract excerpt

Blacks have different dominant polymorphisms in the vitamin D-binding protein (DBP) gene that result in higher bioavailable vitamin D than whites. This study tested whether the lack of association between 25-hydroxyvitamin D (25OHD) and multiple sclerosis (MS) risk in blacks and Hispanics is due to differences in these common polymorphisms (rs7041, rs4588). We recruited incident MS cases and controls (blacks 116...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29414925
DOI: 10.3390/nu10020184
PMCID: PMC5852760

Genes

DBP

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Related research

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Vitamin D-Binding Protein Polymorphisms, 25-Hydroxyvitamin D, Sunshine and Multiple Sclerosis.PMID 29414925Read ↗

MS Sunshine Study: Sun Exposure But Not Vitamin D Is Associated with Multiple Sclerosis Risk in Blacks and Hispanics.Semantic proximity Read ↗

Vitamin D-binding protein and vitamin D status of black Americans and white Americans.Semantic proximity Read ↗

No association between the vitamin D-binding protein (DBP) gene polymorphisms (rs7041 and rs4588) and multiple sclerosis and type 1 diabetes mellitus: A meta-analysis.Semantic proximity Read ↗

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Evidence supports a causal association between allele-specific vitamin D receptor binding and multiple sclerosis among Europeans.Semantic proximity Read ↗

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Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.Semantic proximity Read ↗

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