Article
HIF-1A gene polymorphisms and its protein level in patients with rheumatoid arthritis: a case-control study.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 May 2018
Paradowska-Gorycka Agnieszka, Stypinska Barbara, Pawlik Andrzej, Haladyj Ewa, Romanowska-Próchnicka Katarzyna, Olesinska Marzena
Abstract excerpt
OBJECTIVES: The aim of the study was to identify HIF-1A genetic variants and their possible association with HIF-1α, VEGF, KDR, RORc and Foxp3 protein levels, and susceptibility to and severity of RA. METHODS: The HIF-1A gene polymorphisms were genotyped for 587 RA patients and 341 healthy individuals. The HIF-1α, VEGF, KDR, RORc and Foxp3serum levels were evaluated. RESULTS: Under the codominant model, the...
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