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Article

Nf2 Mutation in Schwann Cells Delays Functional Neural Recovery Following Injury.

Neuroscience - 15 Mar 2018

Truong Kristy, Ahmad Iram, Jason Clark J, Seline Alison, Bertroche Tyler, Mostaert Brian, Van Daele Douglas J, Hansen Marlan R

Abstract excerpt

Merlin is the protein product of the NF2 tumor suppressor gene. Germline NF2 mutation leads to neurofibromatosis type 2 (NF2), characterized by multiple intracranial and spinal schwannomas. Patients with NF2 also frequently develop peripheral neuropathies. While the role of merlin in SC neoplasia is well established, its role in SC homeostasis is less defined. Here we explore the role of merlin in SC responses to...

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Identifiers

PMID: 29408605
DOI: 10.1016/j.neuroscience.2018.01.054
PMCID: PMC5841622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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