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Article

Matrix metalloproteinases in emphysema.

Matrix biology : journal of the International Society for Matrix Biology - 1 Nov 2018

Gharib Sina A, Manicone Anne M, Parks William C

Abstract excerpt

Several studies have implicated a causative role for specific matrix metalloproteinases (MMPs) in the development and progression of cigarette smoke-induced chronic obstructive pulmonary disease (COPD) and its severe sequela, emphysema. However, the precise function of any given MMP in emphysema remains an unanswered question. Emphysema results from the degradation of alveolar elastin - among other possible...

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Identifiers

PMID: 29406250
DOI: 10.1016/j.matbio.2018.01.018
PMCID: PMC6377072

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