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Article

Iron leakage owing to blood-brain barrier disruption in small vessel disease CADASIL.

Neurology - 1 Sept 2020

Uchida Yuto, Kan Hirohito, Sakurai Keita, Arai Nobuyuki, Inui Shohei, Kobayashi Susumu, Kato Daisuke, Ueki Yoshino, Matsukawa Noriyuki

Abstract excerpt

OBJECTIVE: To assess the relationship among iron accumulation, blood-brain barrier (BBB) damage, and cognitive function in patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). METHODS: We enrolled 21 patients with NOTCH3 mutations and 21 age-matched healthy controls in this cross-sectional study. All participants underwent global physical and...

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Identifiers

PMID: 32586899
DOI: 10.1212/WNL.0000000000010148

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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