Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Embryonic Kidney 293 Cells: A Vehicle for Biopharmaceutical Manufacturing, Structural Biology, and Electrophysiology

1 Jan 2018

Abstract excerpt

Mammalian cells, e.g., CHO, BHK, HEK293, HT-1080, and NS0 cells, represent important manufacturing platforms in bioengineering. They are widely used for the production of recombinant therapeutic proteins, vaccines, anticancer agents, and other clinically relevant drugs. HEK293 (human embryonic kidney 293) cells and their derived cell lines provide an attractive heterologous system for the development of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Pancreatic function and diabetes
Share to Viral Infectious Diseases and Gene Expression in Insects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29393161
DOI: 10.1159/000485501

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Embryonic Kidney 293 Cells: A Vehicle for Biopharmaceutical Manufacturing, Structural Biology, and ElectrophysiologyPMID 29393161Read ↗

HEK293 Cell Line as a Platform to Produce Recombinant Proteins and Viral VectorsSemantic proximity Read ↗

The Scattered Twelve Tribes of HEK293Semantic proximity Read ↗

Mammalian Cell Models of the Distal Convoluted Tubule: A Systematic Review of Cell Lines, Culture Condition and Gene ExpressionSemantic proximity Read ↗

The art of CHO cell engineering: A comprehensive retrospect and future perspectivesSemantic proximity Read ↗

Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteinsSemantic proximity Read ↗

Phenotypes and Multi-omics Reveal Changes and Molecular Mechanism of Suspension Adaptation of HEK293 Cells: Structural Remodelling, Metabolic Reconstruction and Stress ResistanceSemantic proximity Read ↗

An improved vector for baculovirus-mediated protein production in mammalian cellsSemantic proximity Read ↗

High‐density transfection with HEK‐293 cells allows doubling of transient titers and removes need for a priori DNA complex formation with PEISemantic proximity Read ↗

Evolution from adherent to suspension – systems biology of HEK293 cell line developmentSemantic proximity Read ↗

A new T-antigen negative HEK293 cell line with improved AAV productivitySemantic proximity Read ↗

Transient Gene Expression in Suspension HEK-293 Cells: Application to Large-Scale Protein ProductionSemantic proximity Read ↗

Evolution from adherent to suspension: systems biology of HEK293 cell line developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.