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Article

Integrative analysis of super enhancer SNPs for type 2 diabetes.

PloS one - 1 Jan 2018

Sun Weiping, Yao Sihong, Tang Jielong, Liu Shuai, Chen Juan, Deng Daqing, Zeng Chunping

Abstract excerpt

Clinical studies in type 2 diabetes (T2D) primarily focused on the single nucleotide polymorphisms (SNPs) located in protein-coding regions. Recently, the SNPs located in noncoding regions have also been recognized to play an important role in disease susceptibility. The super enhancer is a cluster of transcriptional enhancers located in noncoding regions. It plays a critical role in cell-type specific gene...

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Share to Diabetes Mellitus, Type 2
Share to Enhancer Elements, Genetic
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Protein Interaction Maps

Source

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Identifiers

PMID: 29385209
DOI: 10.1371/journal.pone.0192105
PMCID: PMC5792005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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