Article
A Low-Cost Pulse Generator for Exacerbating Muscle Fiber Detachment Phenotypes in Zebrafish.
Zebrafish - 1 Aug 2018
Thomasi Ana Beatriz Delavia, Sonntag Carmen, Pires Danilo Fernando, Zuidema David, Benci Antonio, Currie Peter David, Wood Alasdair John
Abstract excerpt
Muscle fiber detachment from myoseptal boundaries is a common finding in zebrafish models of muscular dystrophies. In some instances, there is a weakening of the interaction between muscle fiber and myosepta, which is yet to manifest as a fiber detachment phenotype. Therefore, to push the fiber detachment of muscle, mutant fish but not their wild-type siblings, beyond their binding threshold, a series of small...
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