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Article

ITPR1 autoimmunity: Frequency, neurologic phenotype, and cancer association

13 Dec 2017

Abstract excerpt

Autoantibodies specific for the neuronal (type 1) isoform of the ubiquitously expressed inositol trisphosphate receptor (ITPR) have been reported in 8 patients to date, 5 with cerebellar ataxia (1 with breast cancer) and 3 with peripheral neuropathy (1 with lung carcinoma and 1 with multiple myeloma).1–4 We report in this study the frequency, neurologic presentations, and oncologic associations of 14...

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PMID: 29379822
DOI: 10.1212/nxi.0000000000000418

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