Article
The biology of CCR5 and CXCR4
1 Mar 2009
Abstract excerpt
PURPOSE OF REVIEW: We discuss the current knowledge concerning the biology of CXCR4 and CCR5 and their roles in HIV-1 infection. RECENT FINDINGS: Important research findings reported in the last 2 years have advanced our knowledge in the field of HIV coreceptors and pathogenesis. Novel methods have been used to crystallize two new members of the G-protein coupled receptors. It has been demonstrated that...
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