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Article

Deleterious genetic variants in ciliopathy genes increase risk of ritodrine-induced cardiac and pulmonary side effects.

BMC medical genomics - 24 Jan 2018

Seo Heewon, Kwon Eun Jin, You Young-Ah, Park Yoomi, Min Byung Joo, Yoo Kyunghun, Hwang Han-Sung, Kim Ju Han, Kim Young Ju

Abstract excerpt

BACKGROUND: Ritodrine is a commonly used tocolytic to prevent preterm labour. However, it can cause unexpected serious adverse reactions, such as pulmonary oedema, pulmonary congestion, and tachycardia. It is unknown whether such adverse reactions are associated with pharmacogenomic variants in patients. METHODS: Whole-exome sequencing of 13 subjects with serious ritodrine-induced cardiac and pulmonary...

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Identifiers

PMID: 29368655
DOI: 10.1186/s12920-018-0323-4
PMCID: PMC5784607

Genes

SERPINA7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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