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Article

Identifying genetic variants associated with ritodrine-induced pulmonary edema.

PloS one - 1 Jan 2020

Lee Seung Mi, Park Yoomi, Kim Young Ju, Hwang Han-Sung, Seo Heewon, Min Byung-Joo, Lee Kye Hwa, Kim So Yeon, Jung Young Mi, Lee Suehyun, Park Chan-Wook, Kim Ju Han, Park Joong Shin

Abstract excerpt

INTRODUCTION: Ritodrine is one of the most commonly used tocolytics in preterm labor, acting as a ß2-adrenergic agonist that reduces intracellular calcium levels and prevents myometrial activation. Ritodrine infusion can result in serious maternal complications, and pulmonary edema is a particular concern among these. The cause of pulmonary edema following ritodrine treatment is multifactorial; however, the...

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Identifiers

PMID: 33166306
DOI: 10.1371/journal.pone.0241215
PMCID: PMC7652239

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