Article
Contribution of angiotensinogen M235T and T174M gene variants and haplotypes to preeclampsia and its severity in (North African) Tunisians.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Jan 2000
Zitouni Hedia, Ben Ali Gannoum Marwa, Raguema Nozha, Maleh Wided, Zouari Ines, Faleh Raja El, Guibourdenche Jean, Almawi Wassim Y, Mahjoub Touhami
Abstract excerpt
BACKGROUND: Preeclampsia (PE) is a pregnancy-associated hypertensive disorder and a leading cause of maternal and neonatal morbidity and mortality. While its pathogenesis remains ill defined, several candidate genes for PE have been identified, but results remain inconclusive. We investigated the association of the angiotensinogen ( AGT) gene variants M235T and T174M with PE, and we analyzed the contribution of...
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