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Article

Association of ACE*(Insertion/Deletion) Variant with the Elevated Risk of Preeclampsia Among Gestational Women.

Biochemical genetics - 1 Oct 2024

El Azab Eman Fawzy, Abd El-Kader Rabab Gad, Elhassan Thoraya Mohamed, Mohammed Ali Sameh A, Shaaban Esraa Ibrahim A, El-Eshmawy Mohamed Adel, Hamid Dina Abdel, El-Beltagy Nanis S, Salem Eman T, Elsaid Afaf M, Elsalahaty Mohamed I, Elshazli Rami M, Anber Nahla

Abstract excerpt

The renin-angiotensin-aldosterone system has an indispensable function in the uteroplacental circulation, placental growth, and blood pressure optimization. The angiotensin I converting enzyme (ACE) gene is a critical integrator for electrolyte balance, and water retention, along with inhibiting preeclampsia. The main goal of this pertaining study is to assess the contribution of ACE*(Ins/Del) variant with the...

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PMID: 38219243
DOI: 10.1007/s10528-023-10620-5

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