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Pertinence between risk of preeclampsia and the renin-angiotensin-aldosterone system (RAAS) gene polymorphisms: an updated meta-analysis based on 73 studies.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology - 1 Dec 2023

Wang Xin, Kong Yujie, Chen Xi, Weng Zhanping, Li Baolai

Abstract excerpt

The aetiological mechanism of preeclampsia (PE) is unclear exactly, so we attempted to investigate the association between susceptibility to preeclampsia and renin-angiotensin-aldosterone system (RAAS) gene polymorphisms to explore the aetiology in terms of genetics. A systematic search was performed in electronic databases to identify relevant studies. Eventually 73 studies were enrolled, odds ratios were...

Topics

Female
Humans
Pregnancy
Renin-Angiotensin System
Pre-Eclampsia
Cytochrome P-450 CYP11B2
Angiotensinogen
Polymorphism, Genetic
Genotype
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36718570
DOI: 10.1080/01443615.2023.2171782

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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