Article
The angiotensinogen gene M235T polymorphism and development of preeclampsia/eclampsia: a meta-analysis and meta-regression of observational studies.
Journal of hypertension - 1 Sept 2008
Zafarmand Mohammad Hadi, Nijdam Marie-Elise, Franx Arie, Grobbee Diederick E, Bots Michiel L
Abstract excerpt
OBJECTIVE: The angiotensinogen gene M235T polymorphism is related to an increased risk of hypertension. Hypertension and pregnancy-induced hypertension have been suggested to share common etiologic factors. We examined whether this mutation also increases the risk of preeclampsia/eclampsia. METHODS: Pubmed/Medline, Web of Science and EMBASE were searched and a hand search of bibliographies was conducted. In all,...
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