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Article

Clinical-genetic model predicts incident impulse control disorders in Parkinson's disease.

Journal of neurology, neurosurgery, and psychiatry - 1 Oct 2016

Kraemmer Julia, Smith Kara, Weintraub Daniel, Guillemot Vincent, Nalls Mike A, Cormier-Dequaire Florence, Moszer Ivan, Brice Alexis, Singleton Andrew B, Corvol Jean-Christophe

Abstract excerpt

OBJECTIVES: Impulse control disorders (ICD) are commonly associated with dopamine replacement therapy (DRT) in patients with Parkinson's disease (PD). Our aims were to estimate ICD heritability and to predict ICD by a candidate genetic multivariable panel in patients with PD. METHODS: Data from de novo patients with PD, drug-naïve and free of ICD behaviour at baseline, were obtained from the Parkinson's...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27076492
DOI: 10.1136/jnnp-2015-312848
PMCID: PMC5098340

Genes

DDC
OPRK1
COMT
DRD2
DRD3
OPRM1
TPH2

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