Article
Genetic Variations of the COL4A1 Gene and Intracerebral Hemorrhage Risk: A Case-Control Study in a Chinese Han Population.
World neurosurgery - 1 Apr 2018
Lin Sen, Xia Chao, He Sha, Yang Jie, Li Hao, Zheng Jun, Liu Ming, You Chao
Abstract excerpt
OBJECTIVE: To investigate the association between single nucleotide polymorphisms or haplotypes of the COL4A1 gene and the risk of intracerebral hemorrhage (ICH). METHODS: We conducted a case-control study that included 181 patients from the Chinese Han population with hypertensive ICH and 197 hypertension patients without ICH. Genomic DNA was extracted by DNA extraction kit, and the 6 single nucleotide...
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