Article
The rs42524 COL1A2 polymorphism is associated with primary intracerebral hemorrhage in a Chinese population.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Dec 2012
Liu Wei, Pang Bo, Lu Ming, Song Hui, Sun Bomin, Zhu Yufang, Pang Qi
Abstract excerpt
Hypertensive arteriosclerosis and amyloid angiopathy account for 78-88% of primary cerebral hemorrhages, and collagen plays a critical role in the pathology of these hemorrhages. The COL1A2 gene on chromosome 7q22.1 has been shown to be associated with intracranial aneurysms. In our study, 393 Han Chinese patients with primary intracerebral hemorrhage (mean age 58.49 ± 9.49 years) and 486 controls (mean age 59.22...
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