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Article

Complete Genomic Assembly of Mauritian Cynomolgus Macaque Killer Ig-like Receptor and Natural Killer Group 2 Haplotypes.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 2024

Prall Trent M, Karl Julie A, Varghese Joshua M, Baker David A, Minor Nicholas R, Raveendran Muthuswamy, Harris R Alan, Rogers Jeffery, Wiseman Roger W, O'Connor David H

Abstract excerpt

Mauritian-origin cynomolgus macaques (MCMs) serve as a powerful nonhuman primate model in biomedical research due to their unique genetic homogeneity, which simplifies experimental designs. Despite their extensive use, a comprehensive understanding of crucial immune-regulating gene families, particularly killer Ig-like receptors (KIR) and NK group 2 (NKG2), has been hindered by the lack of detailed genomic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38639635
DOI: 10.4049/jimmunol.2300856
PMCID: PMC11102026

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