Article
The efficacy of Neurospora in detecting agents that cause aneuploidy.
Mutation research - 1 Jan 2000
Griffiths A J, Brockman H E, DeMarini D M, de Serres F J
Abstract excerpt
A total of 110 agents, 109 chemicals plus gamma-rays, has been tested in a Neurospora pseudowild-type selection system for their ability to induce meiotic aneuploidy. 11 agents were positive, 47 were negative, and 52 were inconclusively tested. The system has a possible role as a short-term test for environmental agents causing human aneuploidy. The advantages of the system are its simplicity and ease of use....
Topics
- Aneuploidy
- Crosses, Genetic
- Genotype
- Mutagenicity Tests
- Mutagens
- Neurospora
- Neurospora crassa
- Species Specificity