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Article

Mutagenicity and mutagenic specificity of metronidazole and niridazole in Neurospora crassa.

Journal of environmental pathology and toxicology - 1 Jan 2000

Ong T, Slade B, de Serres F J

Abstract excerpt

Mutagenicity and mutagenic specificity of niridazole and metronidazole, two chemotherapeutic agents used in the treatment of human parasitic diseases, were studied with the ad-3 test system of Neurospora crassa. The results show that neither compound is mutagenic in resting conidia. In growing vegetative cells, however, both compounds are mutagenic in Neurospora crassa. Genetic analysis of the mutants indicate...

Topics

Genetic Complementation Test
Genotype
Metronidazole
Mutagens
Neurospora
Neurospora crassa
Niridazole

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 156240

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-156240-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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