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Article

Mutagenicity and mutagenic specificity of metronidazole and niridazole in Neurospora crassa.

Journal of toxicology and environmental health - 1 Jan 2000

Ong T, Slade B

Abstract excerpt

Mutagenicity and mutagenic specificity of niridazole and metronidazole, two chemotherapeutic agents used in the treatment of human parasitic diseases, were studied with the ad-3 test system of Neurospora crassa. The results show that neither compound is mutagenic in resting conidia. In growing vegetative cells, however, both compounds are mutagenic in N. crassa. Genetic analysis of the mutants indicated that...

Topics

Genotype
Metronidazole
Mutagens
Neurospora
Neurospora crassa
Niridazole

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 153406
DOI: 10.1080/15287397809529702

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-153406-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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