Article
MicroRNA-19 contributes to the malignant phenotypes of osteosarcoma in vitro by targeting Pax6.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2018
Meng Qingbing, Dai Ming, Nie Xuejun, Zhang Wensheng, Xu Xingli, Li Jian, Mu Hongxin, Liu Xiaolan, Qin Ling, Zhu Xiaoqi, Yan Jun, Zheng Minqian
Abstract excerpt
This study was conducted to detect the expression of miR-19 and Pax6 (Paired box protein 6) in human osteosarcoma cells and the effects on biological characteristics of osteosarcoma cells. Quantitative real-time polymerase chain reaction was used to detect the expression of Pax6 and miR-19 in normal human osteoblasts (hFOB 1.19) and osteosarcoma cell lines (U2OS, Saos-2, and MG-63). Results showed that miR-19 was...
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