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Article

Postnatal tendon growth and remodeling require platelet-derived growth factor receptor signaling

20 Dec 2017

Abstract excerpt

Platelet-derived growth factor receptor (PDGFR) signaling plays an important role in the fundamental biological activities of many cells that compose musculoskeletal tissues. However, little is known about the role of PDGFR signaling during tendon growth and remodeling in adult animals. Using the hindlimb synergist ablation model of tendon growth, our objectives were to determine the role of PDGFR signaling in...

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PMID: 29341790
DOI: 10.1152/ajpcell.00258.2017

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