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Article

The importance of reporting house dust mite endotoxin abundance: impact on the lung transcriptome

22 Apr 2020

Abstract excerpt

The abundance of lipopolysaccharide (LPS) in house dust mite (HDM) preparations is broad and mirrors the variability seen in the homes of people with asthma. LPS in commercially available stocks ranges from 31 to 5,2000 endotoxin units. The influence of vastly different LPS loads on the mechanisms that define the immune and inflammatory phenotype of HDM-challenged mice has not been defined. This aim of the study...

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PMID: 32320279
DOI: 10.1152/ajplung.00103.2020

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