Article
Multi-omics differentially classify disease state and treatment outcome in pediatric Crohn's disease.
Microbiome - 15 Jan 2018
Douglas Gavin M, Hansen Richard, Jones Casey M A, Dunn Katherine A, Comeau André M, Bielawski Joseph P, Tayler Rachel, El-Omar Emad M, Russell Richard K, Hold Georgina L, Langille Morgan G I, Van Limbergen Johan
Abstract excerpt
BACKGROUND: Crohn's disease (CD) has an unclear etiology, but there is growing evidence of a direct link with a dysbiotic microbiome. Many gut microbes have previously been associated with CD, but these have mainly been confounded with patients' ongoing treatments. Additionally, most analyses of CD patients' microbiomes have focused on microbes in stool samples, which yield different insights than profiling...
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