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Article

Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

26 Sept 2012

Abstract excerpt

BACKGROUND: The inflammatory bowel diseases (IBD) Crohn's disease and ulcerative colitis result from alterations in intestinal microbes and the immune system. However, the precise dysfunctions of microbial metabolism in the gastrointestinal microbiome during IBD remain unclear. We analyzed the microbiota of intestinal biopsies and stool samples from 231 IBD and healthy subjects by 16S gene pyrosequencing and...

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PMID: 23013615
DOI: 10.1186/gb-2012-13-9-r79

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