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Weaving New Insights for the Genetic Regulation of Human Cognitive Phenotypes.

Cell - 11 Jan 2018

Mulvey Bernard, Dougherty Joseph D

Abstract excerpt

Psychiatric genetic studies have drawn associations between human cognitive traits and noncoding genomic variants. However, the mechanistic effects of these variants are unclear. By weaving in strands of genomic data from developing human brains, de la Torre-Ubieta et al. tie disease-associated loci to functional enhancers, target genes, and putatively affected cell types.

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PMID: 29328907
DOI: 10.1016/j.cell.2017.12.037

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