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Article

Elevated Proportions of Deleterious Genetic Variation in Domestic Animals and Plants.

Genome biology and evolution - 1 Jan 2018

Makino Takashi, Rubin Carl-Johan, Carneiro Miguel, Axelsson Erik, Andersson Leif, Webster Matthew T

Abstract excerpt

A fraction of genetic variants segregating in any population are deleterious, which negatively impacts individual fitness. The domestication of animals and plants is associated with population bottlenecks and artificial selection, which are predicted to increase the proportion of deleterious variants. However, the extent to which this is a general feature of domestic species is unclear. Here, we examine the...

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Identifiers

PMID: 29325102
DOI: 10.1093/gbe/evy004
PMCID: PMC5786255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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