Article
VDGE: a data repository of variation database for gene-edited animals across multiple species.
Nucleic acids research - 6 Jan 2025
Shi Wenwen, Jin Enhui, Fang Lu, Sun Yanling, Fan Zhuojing, Zhu Junwei, Liang Chengzhi, Zhang Ya-Ping, Zhang Yong Q, Wang Guo-Dong, Zhao Wenming
Abstract excerpt
Gene-edited animals are crucial for addressing fundamental questions in biology and medicine and hold promise for practical applications. In light of the rapid advancement of gene editing technologies over the past decade, a dramatically increased number of gene-edited animals have been generated. Genome editing at off-target sites can, however, introduce genomic variations, potentially leading to unintended...
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