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Article

Increased Genetic Load in Breed Chickens and Reduced Coding Content in Long ROH.

Genome biology and evolution - 31 Jan 2026

Huang Ruoshi, Zhen Ying

Abstract excerpt

Domestic organisms provide valuable models for studying the impact of population bottlenecks, inbreeding, and artificial selection on the accumulation of deleterious variants. While previous studies largely focused on coding variants, our study investigated both coding and noncoding contributions to genetic load in diverse chicken breeds, revealing the consequences of inbreeding and artificial selection on...

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PMID: 41615280
DOI: 10.1093/gbe/evag015
PMCID: PMC12914577

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