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Article

Beta HPV38 oncoproteins act with a hit-and-run mechanism in ultraviolet radiation-induced skin carcinogenesis in mice.

PLoS pathogens - 1 Jan 2018

Viarisio Daniele, Müller-Decker Karin, Accardi Rosita, Robitaille Alexis, Dürst Matthias, Beer Katrin, Jansen Lars, Flechtenmacher Christa, Bozza Matthias, Harbottle Richard, Voegele Catherine, Ardin Maude, Zavadil Jiri, Caldeira Sandra, Gissmann Lutz, Tommasino Massimo

Abstract excerpt

Cutaneous beta human papillomavirus (HPV) types are suspected to be involved, together with ultraviolet (UV) radiation, in the development of non-melanoma skin cancer (NMSC). Studies in in vitro and in vivo experimental models have highlighted the transforming properties of beta HPV E6 and E7 oncoproteins. However, epidemiological findings indicate that beta HPV types may be required only at an initial stage of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29324843
DOI: 10.1371/journal.ppat.1006783
PMCID: PMC5764406

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