Article
Plasmid stability is enhanced by higher-frequency pulses of positive selection.
Proceedings. Biological sciences - 10 Jan 2018
Stevenson Cagla, Hall James P J, Brockhurst Michael A, Harrison Ellie
Abstract excerpt
Plasmids accelerate bacterial adaptation by sharing ecologically important traits between lineages. However, explaining plasmid stability in bacterial populations is challenging owing to their associated costs. Previous theoretical and experimental studies suggest that pulsed positive selection may explain plasmid stability by favouring gene mobility and promoting compensatory evolution to ameliorate plasmid...
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