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Analysis of Somatic DNA Methylation Alterations of Genes Encoding Cell Surface Metallopeptidases in Colorectal Cancer.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Alonso Sergio, González Beatriz, Alibés Andreu, Perucho Manuel

Abstract excerpt

The genome of cancer cells accumulates numerous genetic and epigenetic somatic alterations ultimately conferring capabilities for unrestrained growth, invasion of local tissues, migration, and colonization of distant organs. Many of these new capabilities require the disruption of the cell-to-cell interactions between the cancer cell and its microenvironment. These interactions are mediated, among other factors,...

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PMID: 29318561
DOI: 10.1007/978-1-4939-7595-2_24

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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